Gabriella Lima dos Reis

This study shows that IgA suppresses epithelial proliferation and tumorigenesis by interacting with DMBT1, highlighting its role in maintaining mucosal homeostasis.

This study tracks intestinal CD4+ T cells from suckling to adulthood, showing they adopt a transient cytotoxic-regulatory state at weaning, influenced by microbiota and early-life commensals.

This study uses gene-edited hematopoietic stem cells to create long-lived B lymphocyte protein factories that produce therapeutic antibodies against HIV-1, malaria, and influenza.

This study shows that secreted antibodies significantly diversify primary and secondary humoral immune responses in mice, even at low antibody levels, with implications for vaccine design.

This study uses TRACK mice to show tissue-specific clonal selection and differentiation of CD4+ T cells during influenza infection, revealing organ-specific transcriptional programs and memory formation patterns.