Marwa Saad

This study shows that IgA suppresses epithelial proliferation and tumorigenesis by interacting with DMBT1, highlighting its role in maintaining mucosal homeostasis.

This study tracks intestinal CD4+ T cells from suckling to adulthood, showing they adopt a transient cytotoxic-regulatory state at weaning, influenced by microbiota and early-life commensals.

This study shows that colorectal cancers with different metastatic potential trigger distinct early T cell responses, with non-metastatic tumors inducing cytotoxic T cells and pro-metastatic tumors causing hypoactivated T cells.

This study develops a conditional mouse model to investigate the role of glutathione availability in physiology and disease by expressing a bacterial glutathione-synthesizing enzyme.