Author

Manikandan Periyasamy

Imperial College LondonORCID 0000-0001-7626-2531Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

Simak AliiD· 2 shared Allan BradleyiD· 1 shared Ane Stranger· 1 shared Anthony LimaiD· 1 shared Björn KruspigiD· 1 shared Colin NixoniD· 1 shared Crispin J. MilleriD· 1 shared Daniel J. MurphyiD· 1 shared

Activity by Year

2023-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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2 shared papersCancer Biology

Simak AliORCID

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2 papers

Recent·Most cited

Cancer BiologybioRxivPreprintJul 30, 2024

Human-like APOBEC3 gene expression and anti-viral responses following replacement of mouse Apobec3 with the 7-gene human APOBEC3 locus

Nerissa K Kirkwood, Haydn M Prosser, Melvyn W Yap…·Tim R Fenton

This study creates a mouse model with human APOBEC3 genes to study their expression and anti-viral functions, showing human-like regulation and functional responses.

DOI 10.1101/2024.07.30.605801

mouseexperimental assay

𝕏 PostBluesky

Cancer BiologybioRxivPreprintJul 24, 2023

ERBB signalling contributes to immune evasion in KRAS-driven lung adenocarcinoma

Sarah Laing, Björn Kruspig, Robin Shaw…·Daniel J. Murphy

The paper investigates how ERBB signaling contributes to immune evasion in KRAS-driven lung adenocarcinoma using a novel mouse model and finds that transient ERBB blockade can restore immune surveillance when combined with PD1 blockade.

1 citation

mousebulk RNA-seq

𝕏 PostBluesky