Author
University of AucklandORCID 0000-0001-7747-7745Unclaimed ORCID profile · follow to get notified of new preprints
5 papers
Recent·Most cited
Xiaofan Zhang, Lijie Li, Ziwen Lu…·Tianyu Zhang
This study identifies EthR and EthA genes in Mycobacterium abscessus that mediate resistance to ethionamide, showing EthR is a more dominant resistance factor than NudC.
Jamie R. H. Taka, James Jung, Shuning Guo…·Ghader Bashiri
The paper uses time-resolved cryo-EM to show how acetyl-CoA binding induces conformational changes in ICL2, leading to asymmetric catalytic activity.
Adam J. Fountain, Natalie J.E. Waller, Chen‐Yi Cheung…·Lalita Ramakrishnan
XinYue Wang, William J Jowsey, Chen‐Yi Cheung…·Matthew B. McNeil
The paper identifies vulnerabilities in isoniazid-resistant Mycobacterium tuberculosis strains by analyzing metabolic and transcriptional changes in katG mutants.
Matthew B. McNeil, Laura M. Keighley, Josephine R. Cook…·Gregory Murray Cook
This study uses CRISPR interference to assess the vulnerability and lethality of 96 target genes in Mycobacterium tuberculosis, identifying bactericidal and bacteriostatic effects across different cellular pathways.