Yoshihiro Baba

This study shows that STING inhibits microglial phagocytosis and protects neurons during epileptogenesis by regulating calcium signaling through the STING-STIM1-SOCE axis.

The paper identifies a 5.1-kb deletion in the ARHGAP36 gene as the genetic cause of orange coloration in tortoiseshell and calico cats.

This study shows chronic BCR signaling generates and maintains age-associated B cells from anergic B cells, and Btk inhibition reduces ABCs and lupus pathogenicity.

The paper compares trans-chromosomic rodent models and finds rats show improved somatic hypermutation and class-switch recombination compared to mice.

This study shows that upregulated Fcrl5 disrupts B cell anergy, leading to autoimmunity by activating autoreactive B cells and exacerbating autoimmune disease models.