Author

Johanna H. M. Ehrler

Goethe University FrankfurtORCID 0000-0001-7990-4042Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:human· 2 Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Assay:protein structure· 1 Assay:proteomics· 1

Frequent Co-Authors

Adarsh M. KumariD· 2 shared Ewgenij ProschakiD· 2 shared Julia Schönfeld· 2 shared Kerstin HiesingeriD· 2 shared Stefan KnappiD· 2 shared Aimo KanntiD· 1 shared Arne Hackspacher· 1 shared Astrid Brüggerhoff· 1 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersBiochemistry

Adarsh M. KumarORCID

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2 papers

Recent·Most cited

BiochemistryJournal of Medicinal ChemistryPeer-reviewedJun 18, 2025

STRUCTURE-BASED DESIGN OF PROTACS FOR THE DEGRADATION OF SOLUBLE EPOXIDE HYDROLASE

Julia Schönfeld, Steffen Brunst, Ludmila Ciomirtan…·Kerstin Hiesinger

This paper designs and tests sEH-PROTACs to degrade soluble epoxide hydrolase, identifying PROTAC 23 as effective in degrading sEH in human macrophages.

11 citations

humanprotein structure

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Cell BiologyJournal of Medicinal ChemistryPeer-reviewedMar 12, 2024

Discovery of the sEH Inhibitor Epoxykynin as Potent Kynurenine Pathway Modulator

Lara Dötsch, Caitlin Davies, Elisabeth Hennes…·Herbert Waldmann

The paper identifies epoxykynin as a potent sEH inhibitor that modulates the kynurenine pathway, offering new opportunities to address cancer-induced immune tolerance.

9 citations

humanproteomics

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