Author

Adarsh M. Kumar

Goethe University FrankfurtORCID 0000-0002-8219-0332Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Organism:human· 2 Approach:biophysical modeling· 1 Approach:deep learning· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Assay:protein structure· 1 Assay:proteomics· 1

Frequent Co-Authors

Ewgenij ProschakiD· 3 shared Stefan KnappiD· 3 shared Jan HeeringiD· 2 shared Johanna H. M. EhrleriD· 2 shared Julia Schönfeld· 2 shared Kerstin HiesingeriD· 2 shared Aimo KanntiD· 1 shared Alexandra StolziD· 1 shared

Activity by Year

2024-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

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3 shared papersBiochemistry

Ewgenij ProschakORCID

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3 papers

Recent·Most cited

BiochemistryJournal of Medicinal ChemistryPeer-reviewedJun 18, 2025

STRUCTURE-BASED DESIGN OF PROTACS FOR THE DEGRADATION OF SOLUBLE EPOXIDE HYDROLASE

Julia Schönfeld, Steffen Brunst, Ludmila Ciomirtan…·Kerstin Hiesinger

This paper designs and tests sEH-PROTACs to degrade soluble epoxide hydrolase, identifying PROTAC 23 as effective in degrading sEH in human macrophages.

11 citations

humanprotein structure

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BiochemistryNature CommunicationsPeer-reviewedNov 25, 2024

Targeting LC3/GABARAP for degrader development and autophagy modulation

Martin P. Schwalm, Johannes Dopfer, Adarsh M. Kumar…·Vladimir V. Rogov

The paper evaluates the druggability of LC3/GABARAP for autophagy modulators and identifies ligands that bind to the HP2 pocket of the LIR docking site.

33 citationstop 3%

biophysical modelingdrug response / drug discovery

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Cell BiologyJournal of Medicinal ChemistryPeer-reviewedMar 12, 2024

Discovery of the sEH Inhibitor Epoxykynin as Potent Kynurenine Pathway Modulator

Lara Dötsch, Caitlin Davies, Elisabeth Hennes…·Herbert Waldmann

The paper identifies epoxykynin as a potent sEH inhibitor that modulates the kynurenine pathway, offering new opportunities to address cancer-induced immune tolerance.

9 citations

humanproteomics

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