Kenneth A. Jacobson

This study identifies multiple pathways suppressing stress-induced chronic pain and shows low-dose IL-2 effectively resolves sensitization without relying on opioid or GABA signaling.

This study shows that activating P2Y14R worsens glucose homeostasis and liver steatosis, while antagonizing it improves these conditions in obese mice.

This paper develops a PET tracer for imaging CD73 expression in cancer, showing improved specificity and diagnostic accuracy compared to [18F]FDG.

This study investigates how temperature affects the conformational landscape of the A2A adenosine receptor, showing drug efficacy and membrane mimetic dependence.

This study shows Cannabis terpenes reduce chronic neuropathic pain in mice by activating spinal cord adenosine A2A receptors, with efficacy comparable to morphine.