Author

James A Cain

Department of Infectious Diseases, School of Immunology and Microbial Sciences, King's College London, London, UK;ORCID 0000-0001-8141-0666Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genomics· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:mouse· 1 Approach:statistical model· 1

Frequent Co-Authors

Andrea Martinez-RamasiD· 1 shared Bertille MontibusiD· 1 shared Gilberto BetancoriD· 1 shared Laura ArribasiD· 1 shared Michael H MalimiD· 1 shared Rebecca J. OakeyiD· 1 shared Rocío T. Martínez-NuñeziD· 1 shared Steven LynhamiD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

8 top collaborators · 13 mutual co-author links

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1 shared paperMicrobiology

Andrea Martinez-RamasORCID

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2 papers

Recent·Most cited

MicrobiologybioRxivPreprintNov 11, 2026

POM121 regulates lentiviral nuclear import in a capsid-host factor-dependent manner

Laura Arribas, Andrea Martinez-Ramas, James A Cain…·Gilberto Betancor

This study identifies POM121 as a regulator of lentiviral nuclear import, showing its effect is virus-specific and depends on capsid-host interactions.

DOI 10.64898/2026.11.09.765341

humanexperimental assay

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GenomicsGenome ResearchPeer-reviewedDec 1, 2024

Global identification of mammalian host and nested gene pairs reveal tissue-specific transcriptional interplay

Bertille Montibus, James A. Cain, Rocío T. Martínez-Nuñez, Rebecca J. Oakey

The paper identifies host and nested gene pairs in mouse and human, showing tissue-specific transcriptional co-occurrence and enhanced transcript diversity in host genes.

4 citations

mousehuman

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