Author

Zhuo Chen

Shanghai Jiao Tong UniversityORCID 0000-0001-8247-7387Unclaimed ORCID profile · follow to get notified of new preprints

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Zhuo Chen2 papers · Sichuan University

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 2 Research Focus:cell signaling & trafficking· 2 Approach:experimental assay· 2 Approach:genetic perturbation / CRISPR· 2 Organism:mouse· 2 Approach:biophysical modeling· 1 Assay:bulk RNA-seq· 1 Research Focus:chromatin & epigenetic regulation· 1

Frequent Co-Authors

Changwei LiuiD· 2 shared Hanyu RaoiD· 2 shared Li LiiD· 2 shared Wei‐Qiang GaoiD· 2 shared Wenxin Feng· 2 shared Yue Xu· 2 shared Chunxiao Ma· 1 shared Jing XueiD· 1 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 42 mutual co-author links

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2 shared papersCancer Biology

Changwei LiuORCID

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2 papers

Recent·Most cited

Cancer BiologyOncogenePeer-reviewedJul 22, 2025

NSD2 promotes cell durotaxis and drives the transition from PKD to tubulocystic renal cell carcinoma through integrin/FAK/AKT signaling

Wenxin Feng, Ningyuan Liu, Changwei Liu…·Li Li

This study shows NSD2 promotes cell durotaxis and drives the transition from PKD to TCRCC via integrin/FAK/AKT signaling, with implications for targeted therapies.

2 citations

mousebulk RNA-seq

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Cancer BiologyAdvanced SciencePeer-reviewedJun 18, 2024

Multilevel regulation of NF-kappa B signaling by NSD2 suppresses Kras-driven pancreatic tumorigenesis

Wenxin Feng, Ningning Niu, Ping Lü…·Li Li

This study shows NSD2 acts as a tumor suppressor in Kras-driven pancreatic cancer by regulating NF-kappa B signaling through multiple mechanisms.

7 citations

mouseproteomics

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