Author

Juyeun Lee

Cleveland ClinicORCID 0000-0001-8276-5020Unclaimed ORCID profile · follow to get notified of new preprints

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Juyeun Lee1 paper · Cleveland Clinic

Biology Disciplines

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Cancer Biology· 3

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 3 Organism:human· 3 Research Focus:cancer & tumor microenvironment· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Approach:statistical model· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1

Frequent Co-Authors

Justin Durla LathiaiD· 3 shared Defne BayıkiD· 2 shared Ellen S. HongiD· 2 shared Josephine VolovetziD· 2 shared Kristen E. KayiD· 2 shared Sabrina Z. WangiD· 2 shared András K. PontiiD· 1 shared Andrew DhawaniD· 1 shared

Activity by Year

2024-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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3 shared papersCancer Biology

Justin Durla LathiaORCID

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3 papers

Recent·Most cited

Cancer BiologyNature CancerPeer-reviewedJun 23, 2026

γ-aminobutyric acid receptor B signaling drives glioblastoma in females in an immune-dependent manner

Asmita Pathak, Sravya Palavalasa, Bruno Colon…·Defne Bayık

This study shows GABA receptor B signaling promotes GBM growth in females through immune mechanisms, with sex-specific effects on survival and treatment outcomes.

12 citationstop 1%

humanbulk RNA-seq

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Cancer BiologyJournal of Clinical InvestigationPeer-reviewedNov 19, 2024

Tumor cell-derived spermidine promotes a pro-tumorigenic immune microenvironment in glioblastoma via CD8+ T cell inhibition

Kristen E. Kay, Juyeun Lee, Ellen S. Hong…·Justin Durla Lathia

This study shows that spermidine, a metabolite from glioblastoma cells, suppresses CD8+ T cell function, promoting tumor growth and poor patient outcomes.

33 citationstop 3%

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Cancer BiologyNeuro-Oncology AdvancesPeer-reviewedJan 1, 2024

miR-644a is a tumor cell-intrinsic mediator of sex bias in glioblastoma

Ellen S. Hong, Sabrina Z. Wang, András K. Ponti…·Andrew Dhawan

This study identifies miR-644a as a tumor cell-intrinsic mediator of sex bias in glioblastoma, showing it is more highly expressed in females and its target genes are linked to poorer survival.

1 citation

humanbulk RNA-seq

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