ImmunologyBlood AdvancesPeer-reviewed
CD45-antibody-drug conjugate clears tissue resident myeloid cells from their niches enabling therapeutic adoptive cell transfer
Karin U. Gustafsson, Catherine Rhee, Vanessa Frodermann…·David T. Scadden
This study shows that anti-CD45-ADC clears tissue-resident myeloid cells, enabling efficient replacement with donor cells and reducing atherosclerotic plaque burden.
13 citations