Catherine Rhee

The paper identifies ELMSAN1 as a repressor of nuclear acetyl-CoA production and shows that inhibiting this interaction reprograms cancer cells to a postmitotic state, improving survival in multiple cancer models.

The paper identifies a novel plasmacytoid dendritic cell lineage in mice and humans derived from common lymphoid progenitors, characterized by unique gene expression and functional properties.

This study shows that anti-CD45-ADC clears tissue-resident myeloid cells, enabling efficient replacement with donor cells and reducing atherosclerotic plaque burden.

The paper shows that the epigenetic state of the cell of origin influences susceptibility to Tet2 mutation, with Sox4 promoting dedifferentiation and increased clonal output in hematopoietic stem cells.