Author

Marina Harper

Monash UniversityORCID 0000-0001-8396-0311Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:bacteria (other)· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

Amy Wright· 3 shared John D. BoyceiD· 3 shared Brooke K. HayesiD· 2 shared Sheena McGowaniD· 2 shared David I. RoperiD· 1 shared David L. SteeriD· 1 shared Faye C. MorrisiD· 1 shared Francesca N. Gillett· 1 shared

Activity by Year

2024-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 32 mutual co-author links

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3 shared papersMicrobiology

Amy Wright

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3 papers

Recent·Most cited

MicrobiologyPLoS PathogensPeer-reviewedDec 22, 2025

Comparative analysis of shared and unique mechanisms important for diverse strains of Pasteurella multocida to cause systemic infection in mice

Thomas R. Smallman, Xiaochu Wang, Xenia Kostoulias…·John D. Boyce

This study identifies genes essential for two P. multocida strains to survive in mice, revealing differential requirements for systemic infection despite shared growth genes.

2 citations

mouseexperimental assay

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MicrobiologymBioPeer-reviewedDec 31, 2024

Delivery determinants of an Acinetobacter baumannii type VI secretion system bifunctional peptidoglycan hydrolase.

Valeriya Bezkorovayna, Brooke K. Hayes, Francesca N. Gillett…·John D. Boyce

This study identifies the molecular function and delivery determinants of the T6SS effector Tae17 in Acinetobacter baumannii, showing it is a bifunctional peptidoglycan hydrolase with lytic transglycosylase and amidase activities.

7 citations

humanexperimental assay

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MicrobiologyNature CommunicationsPeer-reviewedOct 8, 2024

Structure of a Rhs effector clade domain identifies new mechanistic insights into type VI secretion system toxin delivery.

Brooke K. Hayes, Marina Harper, Hariprasad Venugopal…·Sheena McGowan

The paper presents the structure of Tse15, a T6SS Rhs effector from Acinetobacter baumannii, revealing a novel mechanism for toxin delivery and activation involving auto-cleavage and domain interaction.

17 citations

bacteria (other)structural biology

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