Yann Bordat

This paper develops IFNAR1 antagonists that selectively block IFNAR signaling in tumor cells, enhancing VSV oncolytic activity in mesothelioma and melanoma models.

The paper shows HIV-1 Tat enhances Mtb and Toxoplasma growth by inhibiting clathrin-mediated endocytosis and autophagy through PI(4,5)P2 binding and palmitoylation.

This paper identifies HCF101 as a novel component of the cytosolic Fe-S assembly pathway in Toxoplasma gondii, essential for parasite survival and a potential drug target.

This study examines how iron depletion affects different Toxoplasma gondii strains, finding that acute strains are more sensitive than cystogenic strains.

This study shows that endoglin deficiency in zebrafish causes hypoxia-driven heart failure and anemia, mirroring features of Hereditary Hemorrhagic Telangiectasia (HHT).