Author

Ryan J. Mulligan

University of VirginiaORCID 0000-0001-8880-6938Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cell Biology· 2

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 2 Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Approach:biophysical modeling· 1 Research Focus:clustering· 1 Research Focus:development & morphogenesis· 1 Research Focus:differential expression· 1 Organism:human· 1

Frequent Co-Authors

Bettina WinckleriD· 2 shared Chan Choo YapiD· 2 shared Laura C. Digilio· 2 shared Isabelle F. Witteveen· 1 shared Lloyd P. McMahoniD· 1 shared Magdalena M. MagajiD· 1 shared Stefanie RedemanniD· 1 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

7 top collaborators · 17 mutual co-author links

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2 shared papersCell Biology

Bettina WincklerORCID

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2 papers

Recent·Most cited

Cell BiologybioRxivPreprintSep 3, 2025

Late endosome transport by RILP-RAB7A promotes dendrite arborization

Chan Choo Yap, Laura C. Digilio, Lloyd P. McMahon…·Bettina Winckler

This study shows that RILP-RAB7A-mediated late endosome transport is essential for dendrite arborization, independent of its role in degradation.

DOI 10.1101/2025.09.03.673267

𝕏 PostBluesky

Cell BiologyJournal of Cell SciencePeer-reviewedApr 5, 2024

Collapse of late endosomal pH elicits a rapid Rab7 response via V-ATPase and RILP.

Ryan J. Mulligan, Magdalena M. Magaj, Laura C. Digilio…·Bettina Winckler

The paper shows that neutralizing late endosomal pH via LLOMe or NH4Cl hyper-activates Rab7 through V-ATPase and RILP, disrupting tubulation and CI-M6PR trafficking.

18 citations

humanproteomics

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