Bettina Winckler

The paper constructs a single-cell signaling atlas of BDNF responses in spinal cord cells, revealing that receptor stoichiometry and cell identity determine signaling outcomes.

This study shows that RILP-RAB7A-mediated late endosome transport is essential for dendrite arborization, independent of its role in degradation.

The paper shows that neutralizing late endosomal pH via LLOMe or NH4Cl hyper-activates Rab7 through V-ATPase and RILP, disrupting tubulation and CI-M6PR trafficking.

The paper investigates RILP knockdown effects in neurons, finding a neuron-specific off-target Golgi disruption that may not reflect RILP's role in endosomal transport.

The paper identifies TrkA as a cargo in sympathetic neuron-derived extracellular vesicles and shows it is retrogradely transported and secreted.

KymoMerge is a Python tool for ImageJ that merges two-channel kymographs from time-lapse movies to analyze co-located tracks.

The paper identifies distinct phases of axon degeneration regulated by p75NTR and DR6, showing calcium flux and spheroid rupture as key events.

This study shows that nestin in immature neurons modulates cdk5 activity, affecting sensitivity to the guidance cue Sema3a, which influences axon growth cone morphology.