Chan Choo Yap

This study shows that RILP-RAB7A-mediated late endosome transport is essential for dendrite arborization, independent of its role in degradation.

The paper shows that neutralizing late endosomal pH via LLOMe or NH4Cl hyper-activates Rab7 through V-ATPase and RILP, disrupting tubulation and CI-M6PR trafficking.

The paper investigates RILP knockdown effects in neurons, finding a neuron-specific off-target Golgi disruption that may not reflect RILP's role in endosomal transport.

KymoMerge is a Python tool for ImageJ that merges two-channel kymographs from time-lapse movies to analyze co-located tracks.