Author

Dhoyazan Azazi

Wellcome/MRC Cambridge Stem Cell InstituteORCID 0000-0001-9085-4031Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Cancer Biology· 2 Genomics· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 3 Organism:mouse· 3 Assay:bulk RNA-seq· 2 Research Focus:cancer & tumor microenvironment· 2 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Research Focus:gene regulatory network inference· 2 Approach:statistical model· 2

Frequent Co-Authors

Brian J.P. HuntlyiD· 3 shared Ryan J. AsbyiD· 3 shared Sarah J. HortoniD· 3 shared George GiotopoulosiD· 2 shared Jaana BagriiD· 2 shared Nathalie SakakiniiD· 2 shared Pedro MadrigaliD· 2 shared Shuchi Agrawal SinghiD· 2 shared

Activity by Year

2020-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 44 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

3 shared papersCancer Biology

Brian J.P. HuntlyORCID

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Cancer BiologyNature CommunicationsPeer-reviewedMay 20, 2025

Genetic or pharmacological inactivation of CREBBP sensitizes B-cell Acute Lymphoblastic Leukemia to Ferroptotic Cell Death upon BCL2 Inhibition

Alicia Garcia-Gimenez, Jonathan E. Ditcham, Dhoyazan Azazi…·Simon E. Richardson

This study identifies CREBBP mutations as a targetable vulnerability in B-ALL, showing that CREBBP inhibition sensitizes these cells to Venetoclax-induced ferroptosis.

19 citationstop 1%

humanbulk RNA-seq

𝕏 PostBluesky

Molecular BiologybioRxivPreprintJan 27, 2025

Delayed Trp53 activation protects Dnmt3a-mutant hematopoietic stem cells from inflammatory attrition.

Ludovica Marando, George Giotopoulos, Pedro Madrigal…·Brian J.P. Huntly

This study shows that DNMT3A R882H mutant HSCs resist inflammatory stress through delayed p53 activation, leading to clonal expansion and increased AML risk.

DOI 10.1101/2025.01.27.635076

mousebulk RNA-seq

𝕏 PostBluesky

Cancer BiologybioRxivPreprintMar 25, 2024

Mutational synergy with CREBBP loss in lymphomagenesis identified through forward insertional mutagenesis in a new DLBCL mouse model

Nathalie Sakakini, Roy Straver, Dhoyazan Azazi…·Brian J.P. Huntly

DOI 10.1101/2024.03.25.586554

mouseexperimental assay

𝕏 PostBluesky

GenomicsBMC BiologyPeer-reviewedSep 23, 2020

Functional signatures of evolutionarily young CTCF binding sites

Dhoyazan Azazi, Jonathan M. Mudge, Duncan T. Odom, Paul Flicek

The paper investigates evolutionarily young CTCF binding sites in two Mus subspecies, finding some functional signatures and a novel immune locus formed by tandem duplication.

14 citations

mouseChIP-seq

𝕏 PostBluesky