Dan J. Hayman

This study shows that suppressing the GCN2-ATF4 pathway extends lifespan in flies, while its activation reduces lifespan, revealing a dual role in aging.

This study shows that knocking down Rbp1, a fly spliceosome component, extends lifespan regardless of when the treatment is initiated.

This study expands and ablates Drosophila haemocytes using genetic tools, finding no effect on adult lifespan or infection resistance but observing pupal lethality in specific genetic backgrounds.

This study shows miR-324 regulates bone homeostasis by controlling osteoblast and osteoclast activity, with its deletion causing increased bone mass and cartilage damage in OA and aging.