Author

Alex Y. H. Wong

Harvard UniversityORCID 0000-0001-9315-4145Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:human· 3 Assay:imaging· 3 Research Focus:cell type annotation· 2 Research Focus:cell-cell communication· 2 Approach:experimental assay· 2 Research Focus:spatial domain detection· 2 Research Focus:clustering· 1 Research Focus:database / resource· 1

Frequent Co-Authors

Peter Karl SorgeriD· 3 shared Clarence YappiD· 2 shared Felix ZhouiD· 2 shared Gaudenz M. DanuseriD· 2 shared Sandro SantagataiD· 2 shared Yi Daniel LuiD· 2 shared Zoltan MaligaiD· 2 shared Ajit J. NirmaliD· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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3 shared papersCancer Biology

Peter Karl SorgerORCID

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3 papers

Recent·Most cited

BioinformaticsbioRxivPreprintSep 30, 2026

✦ In-depth digest

Multiscale harmonization, semantic integration, and immersive exploration of single-cell data in support of novel biological insights

Andreas Bueckle, Chenchen Zhu, Alex Y. H. Wong…·Katy Börner

A free Meta Quest virtual reality app harmonizes CODEX, Visium, Xenium, volumetric immunofluorescence and electron microscopy data from 5 organs into 4 scale levels using the Human Reference Atlas.

1 citation

humanspatial transcriptomics

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Cancer BiologybioRxivPreprintSep 3, 2026

Volumetric Cyclic Immunofluorescence for 3D Spatial Profiling of Tumour, Stroma, and Immune Structures in Human FFPE Tissue

Alex Y. H. Wong, Yi Daniel Lu, Ziyuan Zhao…·Peter Karl Sorger

The paper introduces v-CyCIF, a method for 3D spatial profiling of human FFPE tissue, enabling detailed analysis of tumor, stroma, and immune structures.

DOI 10.64898/2026.05.17.725158

humanimaging

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Cancer BiologyNature MethodsPeer-reviewedSep 29, 2025

Highly Multiplexed 3D Profiling of Cell States and Immune Niches in Human Tumours

Clarence Yapp, Ajit J. Nirmal, Felix Zhou…·Peter Karl Sorger

This paper introduces 3D CyCIF, a method for high-plex 3D profiling of cell states and immune niches in human tumors, revealing detailed spatial interactions and cytokine niches previously unattainable in thin sections.

62 citationstop 1%

humanimaging

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