Abstinence from cocaine self-administration promotes microglia pruning of astrocytes which drives cocaine-seeking behavior
Anze Testen, Jonathan W. VanRyzin, Tania J. Bellinger…·Kathryn J. Reissner
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University of North Carolina at Chapel HillORCID 0000-0001-9388-8958Unclaimed ORCID profile · follow to get notified of new preprints
3 papers
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Anze Testen, Jonathan W. VanRyzin, Tania J. Bellinger…·Kathryn J. Reissner
Janay P. Franklin, Anze Testen, Piotr A. Mieczkowski…·Kathryn J. Reissner
This study identifies molecular changes in astrocytes of the nucleus accumbens in rats following cocaine self-administration and abstinence using RiboTag and RNA-seq.
Ronald Kim, Anze Testen, Eden V. Harder…·Kathryn J. Reissner
The paper examines the effects of long-access cocaine self-administration and abstinence on nucleus accumbens astrocytes in male and female rats, finding significant reductions in male rats but not females.