NeurosciencebioRxivPreprint
Abstinence from cocaine self-administration promotes microglia pruning of astrocytes which drives cocaine-seeking behavior
Anze Testen, Jonathan W. VanRyzin, Tania J. Bellinger…·Kathryn J. Reissner
2 citations
Author
Janay P. Franklin
University of North Carolina at Chapel HillORCID 0000-0002-2444-8403Unclaimed ORCID profile · follow to get notified of new preprints
Biology Disciplines
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2020-2024 · peak 2/yrCo-Author Collaboration Network
10 top collaborators · 34 mutual co-author linksFocal author (center)Selected co-authorORCID co-authorUnlinked name
Curved chords = mutual co-authorship4 papers
Recent·Most cited
- NeurosciencebioRxivPreprint
Investigating cocaine- and abstinence-induced effects on astrocyte gene expression in the nucleus accumbens
Janay P. Franklin, Anze Testen, Piotr A. Mieczkowski…·Kathryn J. Reissner
This study identifies molecular changes in astrocytes of the nucleus accumbens in rats following cocaine self-administration and abstinence using RiboTag and RNA-seq.
1 citation - NeuroscienceeNeuroPeer-reviewed
Abstinence-dependent effects of long-access cocaine self-administration on nucleus accumbens astrocytes are observed in male, but not female rats
Ronald Kim, Anze Testen, Eden V. Harder…·Kathryn J. Reissner
The paper examines the effects of long-access cocaine self-administration and abstinence on nucleus accumbens astrocytes in male and female rats, finding significant reductions in male rats but not females.
23 citations - NeurosciencePsychopharmacologyPeer-reviewed
The synthetically produced predator odor 2,5-dihydro-2,4,5-trimethylthiazoline increases alcohol self-administration and alters basolateral amygdala response to alcohol in rats.
Viren H. Makhijani, Janay P. Franklin, Kalynn J. Van Voorhies…·Joyce Besheer
This study shows that repeated exposure to the predator odor TMT increases alcohol self-administration and alters amygdala response to alcohol in rats, suggesting a link between PTSD-like stress and AUD.
22 citations