Ravi Jagasia

This study identifies homophilic wiring as a principle governing neuronal network topology in vitro, outperforming traditional models in explaining connectivity patterns.

This study identifies a compound that enhances adult hippocampal neurogenesis and improves behavioral pattern separation in both young and aged mice.

This paper develops high-throughput assays to identify and optimize small-molecule stabilizers of misfolded β-glucocerebrosidase, showing NCGC326 reverses pathological accumulation and synergizes with proteostasis regulators.

This study characterizes two novel human GCase antibodies for use in various assays to advance Parkinson disease research.

The paper examines TFEB subcellular localization in Parkinson's and Lewy body disease brains, finding altered distribution linked to disease stages and GBA variants.

The paper identifies a potent ASO targeting UBE3A-ATS in Angelman syndrome patient neurons, showing long-lasting effects in cynomolgus monkeys.

The paper introduces DeePhys, a tool for functional phenotyping of neurons using electrophysiological data, and shows it can predict genotype and age in iPSC-derived DA neurons with the A53T SNCA mutation.