Fumiaki Makino

The paper expresses MreB isoforms from Haloplasma in a synthetic bacterium to study motility, finding distinct movement patterns and force directions.

The paper reports the cryo-EM structure of CYP2C9, revealing a dimer-of-trimers assembly and its stabilization mechanisms.

This study reveals the structural mechanism of MyD88 oligomerization in innate immune signaling using cryo-EM and high-speed AFM.

The paper presents a cryoEM structure of the FliPQR complex in closed form, revealing how FliE opens the periplasmic gate for flagellar rod assembly.

This paper reports cryoEM structures of the flagellar MS-ring and identifies how FliF subunits adopt different conformations to generate three rotational symmetries.

The paper reveals how hibernating ribosomes inhibit RNase I activity to regulate rRNA degradation and biofilm formation in E. coli.

The paper reports the cryo-EM structure of a bacterial adhesin complex and identifies epitopes that affect adhesion and motility in Mycoplasma pneumoniae.

The paper determines the structure of a fibril protein in Spiroplasma using cryo-EM, revealing its helical organization and interactions with MreB filaments.

The paper introduces an epoxidized graphene grid (EG-grid) that improves particle density and orientation in cryoEM, enabling high-resolution structural analysis with fewer micrographs.

The paper presents nine alpaca nanobodies that recognize conserved hidden epitopes on SARS-CoV-2 spike proteins across variants and maintain neutralizing activity against escape mutations.

The paper reports the structure of the LP ring of the bacterial flagellar motor using electron cryomicroscopy, revealing its 26-fold symmetry and intersubunit interactions.