Shifra Ben‐Dor

Patient-derived neuronal models and mouse models reveal that truncated ASXL3 drive epigenetic dysregulation through a gain-of-function mechanism.

This study identifies CD45 as a tuft cell-intrinsic checkpoint that limits intestinal type 2 immunity through an IL-13-induced negative feedback mechanism.

The paper identifies multiple mTOR RNA localization signals in the 5'UTR and 3'UTR that regulate subcellular mTOR localization, protein synthesis, and axonal growth in mice.

This study shows that metacaspases in diatoms are crucial for thermotolerance during marine heat waves, as their absence leads to increased heat sensitivity and oxidative stress.

This study shows IRF1 regulates antiviral immunity through both cytokine signaling and direct promoter binding, affecting gene expression in a context-dependent manner.

This study shows that acetylation of G3BP1 by ELP3 promotes axon regeneration and neuronal recovery after injury.

The paper identifies a core transcriptional program in resistant algal populations during viral infection using transcriptomic analysis of Emiliania huxleyi.

The paper identifies cathepsin X as a conserved cell death protein in algae involved in responses to environmental stress through transcriptome analysis and mutant studies.

The paper identifies Mif as a regulator of tumor immune evasion in low intra-tumor heterogeneity melanoma by analyzing single-cell RNA sequencing data and validating in patient data.

The paper identifies an amphipathic helix as a targeting motif for ER surface proteins in yeast and humans, showing its conservation and role in membrane localization.

This study identifies a fungal commensal that competes with Candida albicans to reduce its burden and mitigate candidiasis in mice.

The paper identifies non-coding variants in the IL18RAP 3'UTR that reduce ALS risk by modulating neuro-inflammation through NF-κB signaling in microglia.

The paper shows that BCKDK compensates for PDK family loss by inactivating PDC, maintaining TCA cycle function and embryonic development in mice.

This study shows that hyaluronan synthesis in the trophectoderm is essential for mouse blastocyst attachment to the uterine epithelium.

This study identifies BACH family members as regulators of VEGFC expression, impacting angiogenesis and lymphangiogenesis in zebrafish and mouse models.