Yardena Samuels

This study shows that epithelial MHC II antigen presentation encodes tissue state and injury signals, maintaining homeostasis and promoting tolerance, while shifting toward damage-associated antigens during inflammation.

The paper identifies Mif as a regulator of tumor immune evasion in low intra-tumor heterogeneity melanoma by analyzing single-cell RNA sequencing data and validating in patient data.

Genesis is a modular protein language model that improves immunogenicity prediction for CD8+ epitopes by integrating pMHC and TCR context, outperforming existing models in precision.

PhISCS-BnB computes the most likely perfect tumor phylogeny from single-cell sequencing data, offering optimality guarantees and significant speed improvements over existing methods.