Robert C. Bauer

This study identifies ADAMTS7's role in promoting atherosclerosis by enhancing smooth muscle cell foam cell formation via an AP-1/PU.1/CD36 pathway.

The paper uses scRNA-seq to study adventitial fibroblast changes in mouse atherosclerosis and identifies SERPINH1 as a key regulator affecting fibroblast function.

This study investigates the depot-specific roles of C/EBPα in white adipose tissue development and metabolism using Cebpa knockout mice, revealing distinct effects on gonadal and inguinal adipose depots and metabolic phenotypes.

The paper identifies CD200 as a specific marker for vascular smooth muscle cells and their derived cells in atherosclerosis using CITE-seq and validates it across multiple techniques.

The paper links LIPA risk alleles to increased monocyte/macrophage LIPA expression, which exacerbates atherosclerosis through enhanced PU.1 binding and altered macrophage function.

The paper fine-maps 77 GWAS loci in the human liver by integrating epigenetic and gene expression data to understand genetic and epigenetic regulation of gene expression.