Gut archaea drive human MAIT cell responses
Natasha Fisher-Pearson, Martin Joseph Lett, Isaac W. D. Maylam…·Jethro S. Johnson
The paper shows that gut archaea produce 5-OP-RU, which activates MAIT cells, linking archaea to human immunity.
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University of OxfordORCID 0000-0001-5816-1657Unclaimed ORCID profile · follow to get notified of new preprints
4 papers
Recent·Most cited
Natasha Fisher-Pearson, Martin Joseph Lett, Isaac W. D. Maylam…·Jethro S. Johnson
The paper shows that gut archaea produce 5-OP-RU, which activates MAIT cells, linking archaea to human immunity.
Sanmoy Pathak, Thea V. Hogan, Sanket Rane…·Benedict P. Seddon
This study maps the ontogeny of Treg subsets in mice, showing naive and effector/memory Treg are continuously replenished by de novo generation, with naive Treg being the main precursor of EM Treg in adults.
Marisol Alvarez-Martinez, Luke S. Cox, Claire F. Pearson…·Anne O’Garra
This study shows Blimp-1 and c-Maf regulate gene networks in T cells to prevent colitis, with distinct roles in controlling inflammatory pathways in mouse models.
Matthew A Jackson, Claire F. Pearson, Nicholas Edward Ilott…·Lilian H. Lam
This paper introduces an optimized IgA-Seq protocol and a novel probability-based scoring method to accurately identify and quantify commensal gut microbiota bound by host immunoglobulins.