Alejandro Suárez‐Bonnet

The paper shows that monocyte-derived alveolar macrophages (mono-AMs) from different insults follow a conserved differentiation blueprint, while fetal-derived AMs show context-dependent changes.

This paper develops an injectable hydrogel platform with poly(orthoester) microparticles for long-term, zero-order drug release, demonstrating in vitro and in vivo efficacy for up to 12 months.

This study shows that Arpc5-containing Arp2/3 complexes are critical for macrophage function and maintaining host-microbiota homeostasis, as their loss leads to intestinal inflammation.

The PRKCA D463H mutation, an inactivating kinase mutation, acts as a gain-of-function oncogenic driver in mice, promoting chondrosarcoma through non-catalytic mechanisms.

This study shows that combining Palbociclib with Telaglenestat prevents acquired resistance in colorectal cancer cells by counteracting metabolic reprogramming.

This study shows Blimp-1 and c-Maf regulate gene networks in T cells to prevent colitis, with distinct roles in controlling inflammatory pathways in mouse models.

This study shows that PKN2 deficiency causes prenatal congenital cardiomyopathy and impairs angiotensin II-induced cardiac hypertrophy in adult mice.