Michael C. Haffner

The paper investigates the role of c-di-AMP and SbtB in cyanobacterial diurnal metabolism, finding that their disruption leads to metabolic dysregulation and diurnal lethality.

The paper shows that c-di-AMP regulates natural competence in cyanobacteria via the ComFB signaling protein, which is essential for pilus biogenesis and DNA uptake.

This study reprograms AR-active prostate cancer to NEPC using ASCL1 and NeuroD1, revealing their role in silencing AR and altering chromatin structure.

This study identifies SbtB as a redox-regulated apyrase that modulates bicarbonate transporter SbtA activity in cyanobacteria by integrating metabolic and carbon status signals.