Oliver Mantovani

The paper investigates the role of c-di-AMP and SbtB in cyanobacterial diurnal metabolism, finding that their disruption leads to metabolic dysregulation and diurnal lethality.

The paper identifies SbtB as a PII-like protein that acts as a unidirectional valve to control bicarbonate transport via SbtA in cyanobacteria, with similar mechanisms observed in Bacillus for ammonium transport.

This study identifies SbtB as a redox-regulated apyrase that modulates bicarbonate transporter SbtA activity in cyanobacteria by integrating metabolic and carbon status signals.