Alessia Ruggieri

ViREn is a two-step method that purifies dengue virus RNA with high purity, revealing a 5-methylcytosine modification mediated by NSUN6 that affects RNA turnover.

This study shows that stress granule formation during FMDV infection is independent of innate immune activation, and that preventing their disassembly reduces viral replication.

The paper shows that the mitochondrial unfolded protein response (UPRmt) interacts with stress granules (SGs) to regulate cellular stress responses and mitochondrial homeostasis.

The paper identifies a mechanism by which PPP1R15A mRNA stability regulates GADD34 expression, controlling the cellular integrated stress response's memory and adaptation to stress.

This study shows that norovirus infection leads to the formation of virus-specific granules and disrupts eIF2α signaling to evade host stress responses.