Johanna Schott

The paper shows that CPSF5 repression leads to transcript shortening and increased pro-inflammatory gene expression in macrophages and sepsis patients.

QuAPPro is an R/shiny app for quantifying and aligning polysome profiles, enabling interactive analysis of UV absorbance and fluorescence data from polysome profiling experiments.

The paper identifies NMD targets and activity in cardiomyocytes using SMG1 inhibition and RNA sequencing, showing conserved targets and reduced efficiency with UPF1/UPF2 knockdown.

ViREn is a two-step method that purifies dengue virus RNA with high purity, revealing a 5-methylcytosine modification mediated by NSUN6 that affects RNA turnover.

This study shows MEK1/2 inhibitors reduce AXIN1 levels in CRC by mTOR-dependent translational repression, not by affecting protein stability.

This study shows that Fibrillarin regulates oncogenic protein pools and ribosomal composition in triple-negative breast cancer by modulating rRNA methylation and RPS28 levels.

This study investigates the interaction between m6A and A-to-I RNA modifications in macrophages, showing that ~60% of genes are m6A-modified and ~12% have A-to-I editing sites, with ~10% overlapping.

The paper identifies a mechanism by which PPP1R15A mRNA stability regulates GADD34 expression, controlling the cellular integrated stress response's memory and adaptation to stress.