Author
National Institutes of HealthORCID 0000-0002-0035-2802Unclaimed ORCID profile · follow to get notified of new preprints
5 papers
Recent·Most cited
Rania Bouzeyen, Nyaradzai Sithole, Avia Watson…·Babak Javid
This study shows that antibodies against Mtb enhance immunity via NLRP3 inflammasome activation in mice, independent of Fc receptors, and this mechanism applies to polyclonal sera in rhesus macaques.
Andrew W. Simonson, Joseph John Zeppa, Allison N. Bucşan…·JoAnne L. Flynn
The paper shows that CD4 T cells and innate CD8+ lymphocytes are essential for IV BCG-induced protection against tuberculosis in macaques.
Natasha S. Kelkar, Nicholas C. Curtis, Urjeet S. Khanwalkar…·Margaret E. Ackerman
The paper identifies a humoral correlate of protection against tuberculosis in humans and non-human primates, showing cross-species and vaccine regimen consistency.
Shu Wang, Amy J. Myers, Edward B. Irvine…·Douglas A. Lauffenburger
The paper uses Markov Fields to integrate multi-modal immune data from vaccinated macaques, identifying critical immune interactions and predicting perturbation effects.
Matthew S. Sutton, Allison N. Bucşan, Chelsea C. Lehman…·Mario Roederer
The paper evaluates the depletion of T cell subsets in nonhuman primates using monoclonal antibodies, finding substantial depletion in blood and tissue with residual cells often remaining in tissue.