Alžběta Roeselová

The paper shows that the ribosome coordinates folding and assembly of a complex protein to enable efficient biogenesis.

This study investigates how GroEL/ES interacts with nascent proteins on ribosomes, showing that GroEL binds and destabilizes substrates, while GroES facilitates partial encapsulation and refolding.

This study shows that the PAN2-PAN3 deadenylation complex can be recruited to specific mRNAs via RNA adaptors, adding to the specificity of mRNA degradation.

The paper investigates how the human ribosome modulates multidomain protein folding by delaying domain docking, contrasting with bacterial ribosomes.

The paper investigates how chaperones coordinate during cotranslational protein folding in bacteria, showing they create a protected space for maturation without destabilizing intermediates.