Piezo2 mediates ultrasonic hearing via cochlear outer hair cells in mice
Jie Li, Shuang Liu, Chenmeng Song…·Wei Xiong
This study shows that Piezo2 in outer hair cells is essential for ultrasonic hearing in mice, but not for low-frequency hearing.
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Tsinghua UniversityORCID 0000-0002-0310-1849Unclaimed ORCID profile · follow to get notified of new preprints
3 papers
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Jie Li, Shuang Liu, Chenmeng Song…·Wei Xiong
This study shows that Piezo2 in outer hair cells is essential for ultrasonic hearing in mice, but not for low-frequency hearing.
Lian Liu, Kuan Li, Linzhi Zou…·Wei Xiong
This study demonstrates that NHEJ-mediated frame restoration can efficiently correct frameshift mutations in vivo, restoring function in a mouse model of Usher syndrome.
Shuang Liu, Shufeng Wang, Linzhi Zou…·Wei Xiong
This study identifies TMC1 as providing a background leak conductance in mouse auditory hair cells, essential for action potential firing and tonotopic organization.