Wobble Vaccines: Complex Vaccine Antigen Pools Promote Increased Antibody Breadth and Cross-Strain Viral Targeting in SARS-CoV-2
Peter R. McIlroy, Wendy M. Zinzow-Kramer, Madison Leigh Ellis…·Matthew Charles Woodruff
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Emory UniversityORCID 0000-0002-0325-5477Unclaimed ORCID profile · follow to get notified of new preprints
4 papers
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Peter R. McIlroy, Wendy M. Zinzow-Kramer, Madison Leigh Ellis…·Matthew Charles Woodruff
Kathryn M. Moore, Stephanie L. Foster, Meenakshi Kar…·Mehul S. Suthar
The paper shows that eosinophils protect against SARS-CoV-2 in vaccinated mice during breakthrough infections by reducing viral burden and limiting dissemination.
Shilpi Jain, Sanjeev Kumar, Lilin Lai…·Mehul S. Suthar
The paper evaluates the effectiveness of an XBB.1.5 monovalent booster vaccine, showing improved antibody binding and neutralization against SARS-CoV-2 Omicron variants.
Barbara Mühlemann, Samuel Wilks, Lauren Baracco…·Derek J. Smith
The paper compares SARS-CoV-2 antigenicity across assays and in human and animal model sera, finding similar immunodominance patterns and antigenic maps but differences in titer magnitude and assay-specific fold change.