G.V. Prateek

The paper analyzes longitudinal body weight data in mice to identify traits linked to lifespan, finding heritable traits associated with energy homeostasis and longevity.

This study investigates how the gut microbiome interacts with aging and dietary restriction in mice, finding that host genetics significantly influence microbiome features and that dietary restriction does not rejuvenate the microbiome.

In 937 genetically diverse female mice, caloric restriction and intermittent fasting extended lifespan, yet bodyweight resilience, immune and red-cell traits, not metabolic improvements, predicted longevity.

This study develops a high-dimensional phenotyping platform to evaluate physiological aging and resilience in mice, finding that aging begins early and resilience declines with age.