Juan Manuel Iglesias‐Artola

This study quantifies lipid sorting during clathrin-mediated endocytosis and finds that lipid asymmetry in the plasma membrane explains observed partitioning, with minimal selectivity for cytoplasmic leaflet lipids compared to non-vesicular trafficking.

This study shows that biomolecular condensates can sustain pH gradients without energy input by neutralizing charges, revealing their role in creating pH microenvironments.

The paper introduces bifunctional ether lipid probes to study intracellular transport kinetics and identifies differences in transport rates between alkyl- and vinyl-linked ether lipids.

The paper quantifies lipid transport between organelles in mammalian cells, revealing non-vesicular transport as a key mechanism for species-specific lipid sorting.

The paper identifies lipoamide as a small molecule that dissolves stress granules and improves outcomes in ALS models by modulating redox-sensitive proteins.

The paper introduces inPhase, a method to accurately determine phase diagrams of protein condensates by using mass and volume conservation, and shows it outperforms fluorescence-based approaches.

The paper shows Hedgehog signaling enhances glycolytic ATP production in Drosophila wing disc tissue, revealing a feedback loop between signaling and energy metabolism.