Argenis Arriojas

This study creates a time-resolved multi-omics map of gene regulation in Toxoplasma gondii by integrating perturbation data with single-cell measurements, revealing regulatory networks and novel interactions.

The paper uses single-cell RNA profiling to show in vivo-derived Toxoplasma bradyzoites undergo two cell cycles, with AP2XI-6 playing a key role in one cycle essential for cyst maturation.

The paper introduces an AI model to analyze mitochondrial morphology in TNBC using TEM images, finding significant structural changes in response to chemotherapy and metastasis.

The paper maps transcriptional and chromatin changes during the Toxoplasma gondii lytic cycle, identifying AP2XII-8 as a key regulator of a ribosome regulon.

This paper introduces a Bayesian model to infer transcription factor activity from gene expression data using logical rules and applies it to bulk and single-cell transcriptomics to study fibroblast plasticity.

The paper uses single-cell RNA sequencing to analyze three Babesia species, identifying conserved and species-specific gene expression patterns across the asexual replication cycle.