NeurosciencebioRxivPreprint
Nuclear tau aggregates inhibit RNA export and form by secondary seeding from cytosolic tau aggregates.
Carolyn J. Decker, Kathleen L. McCann, Evan Lester…·Roy Parker
1 citation
Author
Evan Lester
University of Colorado BoulderORCID 0000-0002-0486-0361Unclaimed ORCID profile · follow to get notified of new preprints
Biology Disciplines
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2021-2026 · peak 2/yrCo-Author Collaboration Network
10 top collaborators · 23 mutual co-author linksFocal author (center)Selected co-authorORCID co-authorUnlinked name
Curved chords = mutual co-authorship4 papers
Recent·Most cited
- NeurosciencebioRxivPreprint
Cytosolic condensates enriched in polyserine repeats are preferred sites of tau fiber propagation
Evan Lester, Meaghan Van Alstyne, Kathleen L. McCann…·Roy Parker
The paper shows polyserine repeats in SRRM2 and PNN recruit to tau aggregates and promote tau fiber propagation in cytoplasmic condensates.
DOI 10.1101/2022.09.22.509111 - Molecular BiologyeLifePeer-reviewed
RNA-BINDING PROTEINS DIRECT MYOGENIC CELL FATE DECISIONS
Joshua Wheeler, Oscar N. Whitney, Thomas Orion Vogler…·Bradley B. Olwin
The paper identifies Hnrnpa2b1 as a key RBP regulating myogenic differentiation through post-transcriptional control in skeletal muscle regeneration.
28 citations - Molecular BiologyNeuronPeer-reviewed
Tau aggregates are RNA-protein assemblies that mis-localize multiple nuclear speckle components
Evan Lester, Felicia K. Ooi, Nadine Bakkar…·Roy Parker
The paper shows that tau aggregates in cells and brains contain RNA and alter nuclear speckle components, affecting pre-mRNA splicing.