Andrea Rodgers Furones

This study shows melanoma suppresses galectin-9 on dendritic cells, and restoring it limits T regulatory cell expansion, suggesting a new therapeutic target.

This study shows that galectin-9 in dendritic cells is necessary for organizing HLA-II at immune synapses, which enhances CD4+ T cell activation and anti-tumor immunity.

This study shows galectin-9 regulates dendritic cell migration by modulating RhoA activity and CD44-mediated rear contractility in both humans and mice.

This study shows that antigen-specific memory NK cells can be generated in ovarian cancer, enhancing their cytotoxicity and tumor reactivity through NKG2C/A-HLA-E/ABC interactions and CXCR2-mediated migration.