Author

Aijun Liu

Chinese PLA General HospitalORCID 0000-0002-0683-4247Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:human· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Assay:cryo-EM· 1 Approach:deep learning· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Ge DongiD· 1 shared Jianlin ZhangiD· 1 shared Junfeng XuiD· 1 shared Lang YangiD· 1 shared Qianru LiiD· 1 shared Richard D. YeiD· 1 shared Weijia ZhangiD· 1 shared Yezhou LiuiD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperCancer Biology

Ge DongORCID

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2 papers

Recent·Most cited

Cancer BiologyFrontiers in ImmunologyPeer-reviewedMay 25, 2026

Tracing the stemness and malignant transition in a heritable colorectal cancer Lynch Syndrome by single-cell RNA-seq analysis

Junfeng Xu, Jianlin Zhang, Yuhang Li…·Zhigang Cai

This paper uses single-cell RNA sequencing to analyze cellular changes in Lynch Syndrome colorectal cancer, identifying cancer stem cells, immune infiltration, and mutation burden during malignant transition.

DOI 10.3389/fimmu.2026.1722806

humanscRNA-seq

𝕏 PostBluesky

BiochemistryCell ReportsPeer-reviewedJun 24, 2024

Structural insights into agonist binding and activation of succinate receptor 1

Aijun Liu, Yezhou Liu, Weijia Zhang, Richard D. Ye

This study presents cryo-EM structures of SUCNR1-Gi complexes bound to succinate and epoxysuccinate, revealing key residues and structural changes involved in agonist binding and activation.

18 citations

humancryo-EM

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