Author
Richard D. Ye
Chinese University of Hong KongORCID 0000-0002-2164-5620Unclaimed ORCID profile · follow to get notified of new preprints
Biology Disciplines
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2023-2025 · peak 3/yrCo-Author Collaboration Network
10 top collaborators · 20 mutual co-author links5 papers
Recent·Most cited
- ImmunologyProceedings of the National Academy of SciencesPeer-reviewed
Structural basis for constitutive activation and CXCL1 recognition of human herpesvirus 8-encoded G protein-coupled receptor KSHV-GPCR
Aijun Liu, Yezhou Liu, Claudia Llinás del Torrent…·Richard D. Ye
This study determines the cryo-EM structures of KSHV-GPCR in complex with Gi and CXCL1, revealing structural mechanisms of constitutive activation and ligand binding.
- ImmunologyCell ReportsPeer-reviewed
Cryo-EM structure of monomeric CXCL12-bound CXCR4 in active state
Yezhou Liu, Aijun Liu, Xinyu Li…·Richard D. Ye
This paper presents a cryo-EM structure of CXCL12-bound CXCR4 in an active state, revealing key interactions that stabilize the ligand-receptor complex.
36 citationstop 2% - BiochemistryCell ReportsPeer-reviewed
Structural insights into agonist binding and activation of succinate receptor 1
Aijun Liu, Yezhou Liu, Weijia Zhang, Richard D. Ye
This study presents cryo-EM structures of SUCNR1-Gi complexes bound to succinate and epoxysuccinate, revealing key residues and structural changes involved in agonist binding and activation.