Weijia Zhang

This study determines the cryo-EM structures of KSHV-GPCR in complex with Gi and CXCL1, revealing structural mechanisms of constitutive activation and ligand binding.

This paper presents a cryo-EM structure of CXCL12-bound CXCR4 in an active state, revealing key interactions that stabilize the ligand-receptor complex.

This study presents cryo-EM structures of SUCNR1-Gi complexes bound to succinate and epoxysuccinate, revealing key residues and structural changes involved in agonist binding and activation.