Author
University of TorontoORCID 0000-0002-0744-9199Unclaimed ORCID profile · follow to get notified of new preprints
7 papers
Recent·Most cited
Yao He, Annie Si Cong Li, Xiaoying Cai…·Z. Hong Zhou
The paper describes a protein fold switch in a bactericidal nanomachine that enables membrane puncture and bactericidal activity.
Kristina M. Sztanko, Taylor J. Ellison, Jill Greenlaw…·Alan R. Davidson
The paper identifies prophage-encoded proteins similar to FimU, which replace bacterial cell surface components to defend against phage infection.
Nolen J. Timmerman, Malcolm Thakurdeen, Robert E.J. Wilson…·Lingling Jin
GNAT identifies homologues and analyzes genomic neighborhoods to provide interactive visualizations and summary analytics for microbial and viral genomes.
Véronique L. Taylor, Pramalkumar H. Patel, Megha Shah…·Karen L. Maxwell
The paper identifies a prophage protein that modulates pilus dynamics to prevent phage progeny destruction, enhancing survival through quorum sensing.
Ranmal Avinash Bandara, Zhichang Peter Zhou, Ziyan Rachel Chen…·Jim Hu
The paper introduces a method for detecting Cas9 gRNAs using fluorophore-labeled DNA oligos to improve gene editing design and targeting efficiency.
Matthew C. Johnson, Eric Laderman, Erin D. Huiting…·Joseph Bondy‐Denomy
The paper identifies two highly conserved core defense hotspots in Pseudomonas aeruginosa containing numerous anti-phage systems, including a newly discovered system called Shango.
Jooyoung Lee, Aamir Mir, Alireza Edraki…·Erik J. Sontheimer
The paper identifies and characterizes two new anti-CRISPR protein families that inhibit type II-C Cas9 systems, showing potent inhibition of NmeCas9 and cross-species activity.