Jarel Elgin Tolentino

The paper analyzes pangolin coronaviruses to identify a key immuno-evasive mutation at spike residue 519, similar to SARS-CoV-2, suggesting independent spillover events from bat reservoirs.

This study identifies the non-spike R204P mutation in the SARS-CoV-2 Omicron XEC variant as a driver of increased inflammation and pathogenicity through NF-κB activation.

This study identifies ACE2 diversity in horseshoe bats and shows bidirectional evolutionary shaping between ACE2 and sarbecovirus spike proteins.

This study identifies structural and phenotypic changes in the RBD loop2 region of HKU5r-CoVs as key factors enabling their emergence in mink and potential zoonotic transmission.

This study investigates the ACE2 tropism of sarbecoviruses across 17 mammals using pseudovirus assays, structural analysis, and phylogenetics to identify genetic factors influencing host range.

This study evaluates the virological properties of SARS-CoV-2 variants KP.3, LB.1, and KP.2.3, finding higher reproduction numbers and immune evasion compared to JN.1.

This study investigates the virological characteristics of the SARS-CoV-2 BA.2.86 variant, finding it has higher reproduction number than EG.5.1 but lower pathogenicity and replication capacity compared to BA.2.

This study investigates the virological properties of the SARS-CoV-2 HK.3 variant, a FLip variant with substitutions S:L455F and S:F456L, to assess its growth advantage.