Soorya Pradeep

V-SWITCH is a fluorescent reporter that detects viral infections by switching from OFF to ON fluorescence, enabling live-cell tracking and screening for antiviral strategies.

The paper maps subcellular localization of human proteins and shows proteome remodeling during viral infection by combining organelle immuno-capture with mass spectrometry.

The paper introduces Mantis, a high-throughput 4D microscope, and shrimPy, software for analyzing 4D data, to study cellular dynamics and responses to perturbations like viral infection.

The paper develops robust virtual staining methods for cellular landmarks using deep learning, showing improved performance across cell types and imaging conditions.

LVING quantifies intracellular growth and degradation by measuring cell mass and transport velocity, revealing structural changes in cell states and drug effects.