Marco Y. Hein

The paper maps subcellular localization of human proteins and shows proteome remodeling during viral infection by combining organelle immuno-capture with mass spectrometry.

This study uses single-cell transcriptomics and proteomics to analyze Vaccinia virus infection dynamics and host response heterogeneity in HeLa and fibroblast cells.

This study uses Perturb-seq to functionally interrogate SARS-CoV-2 host factors in human lung epithelial cells, identifying key factors that influence infection and host response.

The paper introduces dynamo, a framework for estimating RNA velocities and predicting cell fates using single-cell RNA-seq data, applied to various biological processes.

This study uses CRISPR screening and single-cell transcriptomics to analyze the functional roles of host and viral factors in HCMV infection, revealing distinct impacts on infection trajectories.

This study identifies the Hippo pathway's role in regulating sarcomeric gene expression to control myofibril assembly and muscle fiber growth in Drosophila.

The paper introduces MULTI-seq, a method for scalable sample multiplexing in scRNA-seq, enabling analysis of multiple tissues and perturbation experiments while improving data quality.